If you think this won't affect you, you probably haven't spent much time in the totalitarian Constitution-free zones along the gangs' formal turf lines (e.g. "the US-Mexico border"), which were bad enough 30 years ago and are almost certainly worse now. Expect to start seeing the "immigration enforcement" equivalent of DUI checkpoints, especially in cities with substantial Latino populations.
It seems to me that an absolute minimal response requirement is negative social preferencing. ICE agents and other evil-doers shouldn't be invited to social events by their former friends (who should have stopped calling them as of now anyway). They shouldn't be able to get tables in decent restaurants, and if they walk up to fast food counters or sit down on bar stools in uniform, the employees should just silently point to the places' "we reserve the right to refuse service ..." signs. Their clergy should refuse them communion until and unless they're willing to cease, desist, seek forgiveness and make amends. That kind of thing.
I am going with the assumption that few of us will ever find ourselves in a position to actively intervene in an ICE raid in the moment, but being ready and willing to provide refuge as possible to any fleeing victims would be a righteous activity. If you know someone who's particularly at risk, it might be time to have a talk about bugout/communication/rendezvous procedures.
What else? Ideas?